Noun
A subtype of a pathological condition
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More examples (2)
The phenotype is useful in treatment planning while the endotype provides insight in pathophysiological mechanisms of CRS. Therefore, investigations of the pathogenesis and the factors amplifying mucosal inflammation are therefore, of crucial importance for the development of new diagnostic and therapeutic tools.
T2Rs are a novel target for asthma, CRS, and AD treatment independent of the inflammatory profile (type 2 or non–type 2) and could be the perfect example of a smart drug design starting from the endotype and theratype and extending through the drug development program. […] In the future, many new endotypes and theratypes particularly defined by treatment response will be introduced.